Last updated on
Which of the following conditions are not favourable for dissociation of oxygen from oxyhaemoglobin?
Solution:
Dissociation of oxygen from oxyhaemoglobin is favoured by conditions found in tissues where oxygen is needed: low pO₂, high pCO₂, high H⁺ concentration (low pH/acidosis), and high temperature. Conversely, conditions that are not favourable for dissociation (i.e., favour association/loading of oxygen onto haemoglobin) are found in the lungs: high pO₂, low pCO₂, low H⁺ concentration (high pH/alkalosis), and low temperature. Option (4) lists high pO₂ and alkalosis, which are conditions that favour the formation of oxyhaemoglobin, thus are not favourable for its dissociation.